Folding Behaviour and Antibacterial Activity of Ionic Complementary Peptide EAK-16
نویسندگان
چکیده
منابع مشابه
EAK-7 controls development and life span by regulating nuclear DAF-16/FoxO activity.
FoxO transcription factors control development and longevity in diverse species. Although FoxO regulation via changes in its subcellular localization is well established, little is known about how FoxO activity is regulated in the nucleus. Here, we show that the conserved C. elegans protein EAK-7 acts in parallel to the serine/threonine kinase AKT-1 to inhibit the FoxO transcription factor DAF-...
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I herby declare that I am the sole author of this thesis. This is a true copy of the thesis, including any required final revisions, as accepted by my examiners. I understand that my thesis may be made electronically available to the public. iii ABSTRACT Seeding is an important variable in controlling or directing the assembly of peptides. The presence of impurities, responsible for creating a ...
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Insulin regulates development, metabolism, and lifespan via a conserved PI3K/Akt pathway that promotes cytoplasmic sequestration of FoxO transcription factors. The regulation of nuclear FoxO is poorly understood. In the nematode Caenorhabditis elegans, insulin-like signaling functions in larvae to inhibit dauer arrest and acts during adulthood to regulate lifespan. In a screen for genes that mo...
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ژورنال
عنوان ژورنال: Journal of Pharmaceutical Research International
سال: 2021
ISSN: 2456-9119
DOI: 10.9734/jpri/2021/v33i28a31516